Utility of multiparametric renal CT for differentiation of low-grade from high-grade cT1a clear cell renal cell carcinoma.

ABSTRACT:

Objective

To determine if CT can differentiate low-grade from high-grade clear cell renal cell carcinoma (ccRCC) in cT1a solid ccRCC.

Methods and materials

This retrospective cross-sectional study evaluated 78 < 4 cm solid (>25% enhancing) ccRCC in 78 patients with renal CT within 12 months of surgery between January 2016 and December 2019. Two radiologists (R1/R2), blinded to pathology, independently recorded mass:size, calcification, attenuation and heterogeneity (5-point Likert scale) and recorded a 5-point ccRCC CT Score. Multivariate logistic regression (LR) was performed.

Results

There were 64.1% (50/78) low-grade (5/50 Grade 1 and 45/50 Grade 2) and 35.9% (28/78) high-grade (27/28 Grade 3 and 1/28 Grade 4) tumors.Unenhanced CT attenuation was higher (35.9±10.3

SUBMITTER: Pickovsky JS 

PROVIDER: S-EPMC10546453 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature