Circulating calprotectin levels four months after severe and non-severe COVID-19.

ABSTRACT:

Background

Calprotectin is an inflammatory marker mainly released by activated neutrophils that is increased in acute severe COVID-19. After initial recovery, some patients have persistent respiratory impairment with reduced diffusion capacity of the lungs for carbon monoxide (DLCO) months after infection. Underlying causes of this persistent impairment are unclear. We aimed to investigate the correlation between circulating calprotectin, persistent lung functional impairment and intensive care unit (ICU) stay after COVID-19 in two university hospital centres in Switzerland.

Methods

Calprotectin levels were measured in serum from 124 patients (50% male) from the Bern cohort (post-ICU and non-ICU patients) and 68 (76% male) from the Lausanne cohort (only post-ICU patients) fo

SUBMITTER: Abu Hussein N 

PROVIDER: S-EPMC10546778 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature