Radiofrequency ablation for autonomously functioning nodules as treatment for hyperthyroidism: subgroup analysis of toxic adenoma and multinodular goitre and predictors for treatment success.

ABSTRACT:

Purpose

Treatment of hyperthyroidism caused by autonomously functioning thyroid nodules (AFTN) with ¹³¹I often leads to undesirable hypothyroidism. Radiofrequency ablation (RFA) has emerged as a promising alternative. This retrospective analysis aimed to examine the efficacy of, and postprocedural hypothyroidism after, RFA for AFTN.

Methods

Patients with hyperthyroidism caused by AFTN and treated with RFA were included if follow-up of at least 1 year was available. Cure was defined as thyroid medication-free biochemical euthyroidism. To predict cure, patient and treatment factors were analysed. A distinction was made between solitary toxic adenoma (STA) and toxic multinodular goitre (TMG).

Results

Forty-eight patients (36 STA, 12 TMG) were included. One yea

SUBMITTER: van der Meeren MMD 

PROVIDER: S-EPMC10547644 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature