A nomogram predicts early neurological deterioration after mechanical thrombectomy in patients with ischemic stroke.

ABSTRACT:

Introduction

Early neurological deterioration (END) is common in acute ischemic stroke and is directly associated with poor outcome after stroke. Our aim is to develop and validate a nomogram to predict the risk of END after mechanical thrombectomy (MT) in acute ischemic stroke patients with anterior circulation large-vessel occlusion.

Methods

We conducted a real-world, multi-center study in patients with stroke treated with mechanical thrombectomy. END was defined as a worsening by 2 or more NIHSS points within 72-hour after stroke onset compared to admission. Multivariable logistic regression was used to determine the independent predictors of END, and the discrimination of the scale was assessed using the C-index. Calibration curves were constructed to evaluate the calibr

SUBMITTER: Wu K 

PROVIDER: S-EPMC10548384 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature