Mechanical Power Density Predicts Prolonged Ventilation Following Double Lung Transplantation.

ABSTRACT: Prolonged mechanical ventilation (PMV) after lung transplantation poses several risks, including higher tracheostomy rates and increased in-hospital mortality. Mechanical power (MP) of artificial ventilation unifies the ventilatory variables that determine gas exchange and may be related to allograft function following transplant, affecting ventilator weaning. We retrospectively analyzed consecutive double lung transplant recipients at a national transplant center, ventilated through endotracheal tubes upon ICU admission, excluding those receiving extracorporeal support. MP and derived indexes assessed up to 36 h after transplant were correlated with invasive ventilation duration using Spearman's coefficient, and we conducted receiver operating characteristic (ROC) curve analysis to evalua

SUBMITTER: Ghiani A 

PROVIDER: S-EPMC10548550 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature