Declining Incidence of Postoperative Neonatal Brain Injury in Congenital Heart Disease.

ABSTRACT:

Background

Brain injury is common in neonates with complex neonatal congenital heart disease (CHD) and affects neurodevelopmental outcomes.

Objectives

Given advancements in perioperative care, we sought to determine if the rate of preoperative and postoperative brain injury detected by using brain magnetic resonance imaging (MRI) and associated clinical risk factors have changed over time in complex CHD.

Methods

A total of 270 term newborns with complex CHD were prospectively enrolled for preoperative and postoperative brain MRIs between 2001 and 2021 with a total of 466 MRI scans. Brain injuries in the form of white matter injury (WMI) or focal stroke and clinical factors were compared across 4 epochs of 5-year intervals with logistic regression.

Results

Rates

SUBMITTER: Peyvandi S 

PROVIDER: S-EPMC10548869 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature