Association between pertussis vaccination in infancy and childhood asthma: A population-based record linkage cohort study.

ABSTRACT:

Background

Asthma is among the commonest noncommunicable diseases of childhood and often occurs with other atopic comorbidities. A previous case-control study found evidence that compared to children who received acellular pertussis (aP) vaccines in early infancy, children who received one or more doses of whole-cell pertussis (wP) vaccine had lower risk of developing IgE-mediated food allergy. We hypothesized that wP vaccination in early infancy might protect against atopic asthma in childhood.

Methods

Retrospective record-linkage cohort study of children between 5 and < 15 years old and born between January 1997, and December 1999, in the Australian states of Western Australia (WA) and New South Wales (NSW), receiving wP versus aP vaccine as the first pertussis vaccine dos

SUBMITTER: Perez Chacon G 

PROVIDER: S-EPMC10550153 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature