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A case report on POEMS syndrome with high parathyroid hormone and repeated surgery, a rare presentation of a rare disease.


ABSTRACT:

Introduction

Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is a rare multisystemic disease that is named for its constellation which can easily be mistaken for other disorders.

Case presentation

In present study we evaluated a 39-year-old man with hypercalcemia and parathyroid hormone. He underwent two failed surgeries for parathyroid adenoma but due to the presence of other features of the syndrome, a diagnosis of POEMS syndrome was made. His symptoms were multiple peripheral neuropathies, monoclonal plasma cell proliferative disorder, multiple bony lesions alongside endocrinopathy, lymphadenopathy, extravascular volume overload, mildly hypocellular marrow with polymorphic population, trilineage hematopoiesis, and progre

SUBMITTER: Yaseri A 

PROVIDER: S-EPMC10551613 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature