Complete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial.

ABSTRACT:

Background

The impact of complete revascularization (CR) on angina-related health status (symptoms, function, quality of life) in chronic coronary disease (CCD) has not been well studied.

Objectives

Among patients with CCD randomized to invasive (INV) vs conservative (CON) management in ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches), we compared the following: 1) the impact of anatomic and functional CR on health status compared with incomplete revascularization (ICR); and 2) the predicted impact of achieving CR in all INV patients compared with CON.

Methods

Multivariable regression adjusting for patient characteristics was used to compare 12-month health status after independent core laboratory-defined CR vs IC

SUBMITTER: Mavromatis K 

PROVIDER: S-EPMC10551823 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature