Prevalence and cost of sickle cell disease in France: real-world analysis using data from the Echantillon Generaliste des Beneficiaires.

ABSTRACT: Sickle cell disease (SCD) is a genetic disorder of the hemoglobin resulting in chronic anemia, hemolysis, and vaso-occlusions. Its treatment mostly relies on hydroxycarbamide, transfusions, and stem cell transplantation. This study aimed at describing the epidemiology and management of SCD in adolescent and adult patients in France. This was a retrospective study performed among SCD patients aged ≥12 years between 2016 and 2018 and controls. SCD patients were matched on a 1:3 ratio with a group of individuals with no diagnosis of SCD, referred as control group. The matching of SCD patients and controls was a direct matching based on age, sex, CMU-c status (which corresponds to free-of-charge complementary coverage for people with low resources) and geographical region of residence. SCD pat

SUBMITTER: Beillat M 

PROVIDER: S-EPMC10552641 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature