Assessing the magnitude of changes from protocol to publication-a survey on Cochrane and non-Cochrane Systematic Reviews.

ABSTRACT:

Objective

To explore differences between published reviews and their respective protocols in a sample of 97 non-Cochrane Systematic Reviews (non-CSRs) and 97 Cochrane Systematic Reviews (CSRs) in terms of PICOS (Patients/Population, Intervention, Comparison/Control, Outcome, Study type) elements and the extent to which they were reported.

Study design and setting

We searched PubMed and Cochrane databases to identify non-CSRs and CSRs that were published in 2018. We then searched for their corresponding Cochrane or PROSPERO protocols. The published reviews were compared to their protocols. The primary outcome was changes from protocol to review in terms of PICOS elements.

Results

We identified a total of 227 changes from protocol to review in PICOS elements, 1.11 (Stan

SUBMITTER: Siebert M 

PROVIDER: S-EPMC10552742 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature