Additional predictors of the lower limit of cerebral autoregulation during cardiac surgery.

ABSTRACT:

Objectives

The lower limit of autoregulation (LLA) of cerebral blood flow was previously shown to vary directly with the Ambulatory Arterial Stiffness Index (AASI) redefined as 1-regression slope of DBP-versus-SBP readings invasively measured from the radial artery before the bypass. We aimed expanding the predictive capacity of the LLA with AASI by combining it with additional predictors and provide new indications whether mean arterial pressure (MAP) is above/below the LLA.

Design and method

In 181 patients undergoing cardiac surgery, mean (SD) age 71 (8) years), we identified from the demographic, preoperative and intraoperative characteristics independent and statistically significant 'single predictors' of the LLA (including AASI). This was achieved using multivariate l

SUBMITTER: Gavish B 

PROVIDER: S-EPMC10552816 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature