Continuous vs. intermittent terlipressin infusion for portal hypertension: a systematic review and meta-analysis.

ABSTRACT:

Background

Portal hypertension, a major complication of chronic liver disease, often leads to life-threatening variceal bleeding, managed effectively with vasoactive drugs like terlipressin. However, the most optimal method of terlipressin administration, continuous versus intermittent infusion, remains a subject of debate, necessitating this systematic review and meta-analysis for evidence-based decision-making in managing this critical condition.

Methods

This systematic review and meta-analysis adhered to the PRISMA standards and explored multiple databases until 6 April 2023, such as MEDLINE through PubMed, Scopus, Web of Science, and CENTRAL. Independent reviewers selected randomized controlled trials (RCTs) that met specific inclusion criteria. After assessing study qua

SUBMITTER: Hassan M 

PROVIDER: S-EPMC10553058 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature