Social affective behaviors among female rats involve the basolateral amygdala and insular cortex.

ABSTRACT: The ability to detect, appraise, and respond to another's emotional state is essential to social affective behavior. This is mediated by a network of brain regions responsible for integrating external cues with internal states to orchestrate situationally appropriate behavioral responses. The basolateral amygdala (BLA) and the insular cortex are reciprocally connected regions involved in social cognition and prior work in male rats revealed their contributions to social affective behavior. We investigated the functional role of these regions in female rats in a social affective preference (SAP) test in which experimental rats approach stressed juvenile but avoid stressed adult conspecifics. In separate experiments, the BLA or the insula were inhibited by local infusion of muscimol (100ng/s

SUBMITTER: Djerdjaj A 

PROVIDER: S-EPMC10553809 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature