The Association Between Thyroid Stimulating Hormone and Depression: A Historical Cohort Study.

ABSTRACT:

Objective

To investigate the association between thyroid-stimulating hormone (TSH) and clinically relevant depression (CRD) in a population-based study.

Patients and methods

Adult patients (≥18 years of age) who received care at Mayo Clinic in Rochester, Minnesota, and completed a TSH and Patient Health Questionnaire - 9 (PHQ-9) within 6 months of each other, between July 8, 2017, and August 31, 2021, were included. Demographics, medical comorbidities, thyroid function laboratory data, psychotropic medications, presence of primary thyroid disorder, thyroid hormone replacement (T4 and/or T3), and mood disorder diagnoses (using International Classification of Diseases, 10^th version, Clinical Modifications codes) were extracted electronically. The primary outcome, CR

SUBMITTER: Kumar R 

PROVIDER: S-EPMC10554405 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature