Contrast-enhanced ultrasonography-based renal blood perfusion in brain-dead donors predicts early graft function.

ABSTRACT:

Purpose

The aim of this study was to quantify renal microcirculatory perfusion in braindead donors using contrast-enhanced ultrasonography (CEUS), and to establish an accurate, noninvasive, and convenient index for predicting delayed graft function (DGF) post-transplantation.

Methods

In total, 90 brain-dead donor kidneys (training group, n=60; validation group, n=30) examined between August 2020 and November 2022 were recruited in this prospective study. CEUS was performed on the kidneys of brain-dead donors 24 hours before organ procurement and time-intensity curves were constructed. The main measures were arrival time, time to peak, and peak intensity of the kidney segmental arteries, cortex, and medulla. Recipients were divided into DGF and non-DGF groups according to ear

SUBMITTER: He W 

PROVIDER: S-EPMC10555683 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature