Estimating the effect of physical activity on cognitive function within the UK Biobank cohort.

ABSTRACT:

Background

Physical activity (PA) has been associated with benefits for cognitive function (CF), but previous estimates of the strength of this relationship may have been biased due to limitations in statistical modelling practices that are common among observational studies. We aimed to address this by using a rigorously constructed conceptual causal model to guide an empirical analysis estimating the effect of PA on CF in the UK Biobank cohort of middle-aged and older adults.

Methods

This study analysed a subsample of 334 227 adults from the UK Biobank prospective cohort study. PA was measured subjectively by self-report and by device using accelerometry, and CF was measured using objective cognitive tests. Composite CF measures were derived to represent general and domain

SUBMITTER: Campbell T 

PROVIDER: S-EPMC10555922 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature