Electro-oxidation sensing of sumatriptan in aqueous solutions and human blood serum by Zn(II)-MOF modified electrochemical delaminated pencil graphite electrode.

ABSTRACT: An electrochemical sensory platform is presented for determination of sumatriptan (SUM) in aqueous solutions and human blood serum. A pencil graphite electrode (PGE) was electrochemically delaminated by cyclic voltammetry technique, and then further modified using nanoparticles of a zinc-based metal-organic framework (Zn(II)-MOF). The fabricated Zn(II)-MOF/EDPGE electrode was utilized for sensitive electrochemical detection of SUM via an electro-oxidation reaction. The Zn(II)-MOF was hydrothermally synthesized and characterized by various techniques. The electrochemical delamination of PGE results in a porous substrate, facilitating the effective immobilization of the modifier. The designed sensor benefits from both enhanced surface area and an accelerated electron transfer rate, as eviden

SUBMITTER: Saghatforoush L 

PROVIDER: S-EPMC10556131 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature