Recurring Pancreatic Neuroendocrine Tumor: Timing and Pattern of Recurrence and Current Treatment.

ABSTRACT:

Objective

The objective of this study was to describe the pattern of recurrence, treatments received, as well the oncological outcomes, of pancreatic neuroendocrine tumors (PanNETs) following curative surgery.

Background

PanNETs recur in 10% to 15% of cases following surgery. Information on the natural history and management of recurring disease is lacking.

Materials and methods

Patients with PanNET that underwent curative surgery at 4 institutions between 2000 and 2019 were identified. Patients with poorly differentiated tumors, unknown tumor grade and differentiation, hereditary syndromes, unknown margin or R2 status, metastatic, and those that had neoadjuvant treatment or perioperative mortality were excluded. Clinical variables were assessed including first site o

SUBMITTER: Pulvirenti A 

PROVIDER: S-EPMC10556340 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature