Progression of radiographic fibrosis in rheumatoid arthritis-associated interstitial lung disease.

ABSTRACT:

Background and objectives

Preclinical interstitial lung disease (pILD) may represent the early stages of rheumatoid arthritis-associated interstitial lung disease (RA-ILD). However, the characteristics, clinical outcomes, and risk factors associated with fibrosis progression in RA-ILD, including pILD and ILD, remain poorly understood.

Methods

Baseline data were compared between patients with RA-ILD and those with RA alone. Multivariate logistic regression and Cox regression analyses were performed to identify risk factors associated with the prevalence and imaging progression of RA-ILD, respectively.

Results

Among the 371 enrolled RA patients, 32.3% had RA-ILD. Multiple logistic regression analyses identified age over 60.0 years (OR 2.22), smoking (OR 2.09), diabetes

SUBMITTER: Chai D 

PROVIDER: S-EPMC10556458 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature