Mortality in patients with end-stage liver disease above model for end-stage liver disease 3.0 of 40.

ABSTRACT:

Background and aims

Since the implementation of the model for end-stage liver disease (MELD) score to determine waitlist priority for liver transplant (LT) in 2002, the score has been capped at 40. Recently, the MELD 3.0 score was proposed to improve upon MELD-Na. Here, we examine waitlist mortality and LT outcomes in patients with MELD 3.0 ≥ 40 to assess the potential impact of uncapping the score.

Approach and results

Adult waitlist registrations for LT from January 2016 to December 2021 were identified in the registry data from the Organ Procurement and Transplant Network. All MELD 3.0 scores were calculated at registration and thereafter. Waitlist mortality for up to 30 days was calculated as well as post-LT survival. There were 54,060 new waitlist registrations during t

SUBMITTER: Kim WR 

PROVIDER: S-EPMC10556544 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature