Cobalt ferrite nanoparticle for the elimination of CD133+CD44⁺ and CD44⁺CD24^-, in breast and skin cancer stem cells, using non-ionizing treatments.

ABSTRACT:

Background

Cancer stem cells (CSCs) are the most challenging issue in cancer treatment, because of their high resistance mechanisms, that can cause tumor recurrence after common cancer treatments such as drug and radiation based therapies, and the insufficient efficiency of common treatments in CSCs removal and the recurrence of tumors after these treatments, it is essential to consider other methods, including non-ionizing treatments likes light-based treatments and magnetic hyperthermia (MHT).

Method and material

After synthesis, characterization and investigation, the toxicity of novel on A375 and MAD-MB-231 cell lines, magnetic hyperthermia and light-based treatments were applied. MTT assay and flow cytometry was employed to determine cell survival. the influence of comb

SUBMITTER: Khalili Najafabad B 

PROVIDER: S-EPMC10556613 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature