Chordal force profile after neochordal repair of anterior mitral valve prolapse: An ex vivo study.

ABSTRACT:

Objective

This study aimed to biomechanically evaluate the force profiles on the anterior primary and secondary chordae after neochord repair for anterior valve prolapse with varied degrees of residual mitral regurgitation using an ex vivo heart simulator.

Methods

The experiment used 8 healthy porcine mitral valves. Chordal forces were measured using fiber Bragg grating sensors on primary and secondary chordae from A2 segments. The anterior valve prolapse model was generated by excising 2 primary chordae at the A2 segment. Neochord repair was performed with 2 pairs of neochords. Varying neochord lengths simulated postrepair residual mitral regurgitation with regurgitant fraction at >30% (moderate), 10% to 30% (mild), and <10% (perfect repair).

Results

Regurgitant frac

SUBMITTER: Yajima S 

PROVIDER: S-EPMC10556825 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature