High-Throughput Determination of Stern-Volmer Quenching Constants for Common Photocatalysts and Quenchers.

ABSTRACT: Mechanistic information on reactions proceeding via photoredox catalysis has enabled rational optimizations of existing reactions and revealed new synthetic pathways. One essential step in any photoredox reaction is catalyst quenching via photoinduced electron transfer or energy transfer with either a substrate, additive, or cocatalyst. Identification of the correct quencher using Stern-Volmer studies is a necessary step for mechanistic understanding; however, such studies are often cumbersome, low throughput and require specialized luminescence instruments. This report describes a high-throughput method to rapidly acquire a series of Stern-Volmer constants, employing readily available fluorescence plate readers and 96-well plates. By leveraging multichannel pipettors or liquid dispensing

SUBMITTER: Motz RN 

PROVIDER: S-EPMC10557125 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature