Association of N-terminal pro-B-type natriuretic peptide levels and mortality risk in acute myocardial infarction across body mass index categories: an observational cohort study.

ABSTRACT:

Background

The prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) across body mass index (BMI) categories in patients with acute myocardial infarction (AMI) is unclear. We aimed to assess the predictive value of NT-proBNP levels and identify the best cutoff values for mortality risk prediction across BMI categories in AMI.

Methods

We analyzed 4677 patients with AMI from the Cardiovascular Centre Beijing Friendship Hospital Database Bank. Patients were classified into underweight (< 18.5 kg/m²), normal-weight (18.5-23.9 kg/m²), overweight (24-27.9 kg/m²), and obese (≥ 28 kg/m²) groups. The association between NT-proBNP (ln-transformed) and mortality was investigated using Cox regression and stratified by BMI.<

SUBMITTER: Wang M 

PROVIDER: S-EPMC10557200 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature