Network meta-analysis on efficacy and safety of different biologics for ulcerative colitis.

ABSTRACT:

Background

Therapeutic options for ulcerative colitis (UC) have increased since the introduction of biologics a few decades ago. Due to the wide range of biologics available, physicians have difficulty in selecting biologics and do not know how to balance the best drug between clinical efficacy and safety. This study aimed to compare the efficacy and safety of biologics in treating ulcerative colitis.

Methods

In this study, eight electronic databases (PubMed, Web of Science, Cochrane, Embase, Sinomed, China National Knowledge Infrastructure, Chongqing VIP Information, and WanFang Data) were searched to collect eligible studies without language restrictions. Retrieved 1 June 2023, from inception. All articles included in the mesh analysis are randomised controlled trials (RCT

SUBMITTER: Chu X 

PROVIDER: S-EPMC10557260 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature