Online adaptive radiotherapy for bladder cancer using a simultaneous integrated boost and fiducial markers.

ABSTRACT:

Purpose

The aim was to assess the feasibility of online adaptive radiotherapy (oART) for bladder cancer using a focal boost by focusing on the quality of the online treatment plan and automatic target delineation, duration of the workflow and performance in the presence of fiducial markers for tumor bed localization.

Methods

Fifteen patients with muscle invasive bladder cancer received daily oART with Cone Beam CT (CBCT), artificial intelligence (AI)-assisted automatic delineation of the daily anatomy and online plan reoptimization. The bladder and pelvic lymph nodes received a total dose of 40 Gy in 20 fractions, the tumor received an additional simultaneously integrated boost (SIB) of 15 Gy. The dose distribution of the reference plan was calculated for the daily anatomy,

SUBMITTER: Azzarouali S 

PROVIDER: S-EPMC10557331 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature