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Dataset Information

Occurrence of SARS-CoV-2 viremia is associated with genetic variants of genes related to COVID-19 pathogenesis.


ABSTRACT:

Introduction

SARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity.

Materials and methods

Retrospective observational study including 340 patients hospitalized for COVID-19 in the University Hospital La Princesa between March 2020 and December 2021, with at least one viremia determination. Positive viremia was considered when viral load was above the quantifiable threshold (20 copies/ml). A total of 38 SNPs were genotyped. To study their association with viremia a multivariate logistic regression was performed.

Results

The mean age of the studied population was 64.5 years (SD 16.6), 60.9% pat

SUBMITTER: Roy-Vallejo E 

PROVIDER: S-EPMC10557488 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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