An updated database of virus circular RNAs provides new insights into the biogenesis mechanism of the molecule.

ABSTRACT: Virus circular RNAs (circRNA) have been reported to be extensively expressed and play important roles in viral infections. Previously we build the first database of virus circRNAs named VirusCircBase which has been widely used in the field. This study significantly improved the database on both the data quantity and database functionality: the number of virus circRNAs, virus species, host organisms was increased from 46440, 23, 9 to 60859, 43, 22, respectively, and 1902 full-length virus circRNAs were newly added; new functions were added such as visualization of the expression level of virus circRNAs and visualization of virus circRNAs in the Genome Browser. Analysis of the expression of virus circRNAs showed that they had low expression levels in most cells or tissues and showed strong e

SUBMITTER: Fu P 

PROVIDER: S-EPMC10557547 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature