BAllC and BAllCools: Efficient Formatting and Operating for Single-Cell DNA Methylation Data.

ABSTRACT:

Motivation

With single-cell DNA methylation studies yielding vast datasets, existing data formats struggle with the unique challenges of storage and efficient operations, highlighting a need for improved solutions.

Results

BAllC (Binary All Cytosines) emerges as a tailored binary format for methylation data, addressing these challenges. BAllCools, its complementary software toolkit, enhances parsing, indexing, and querying capabilities, promising superior operational speeds and reduced storage needs.

SUBMITTER: Tian W 

PROVIDER: S-EPMC10557610 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature