The metastasis patterns and their prognostic features in patients with de novo metastatic breast cancer of different ages.

ABSTRACT:

Purpose

The prognostic outcomes of metastasis patterns in patients with de novo metastatic breast cancer (dnMBC) of different ages are unknown. Our study used a large-scale data to investigate the metastasis patterns and prognostic features in dnMBC of different ages.

Methods

Total 24,698 women with dnMBC in the Surveillance, Epidemiology and End Results database (2010-2018) were divided into three groups by age. Chi-squared test was used to compare metastasis patterns and logistic regression was performed to investigate the risk of age and specific organ metastases. Kaplan-Meier survival curves were used to compare the overall survival.

Results

In three groups, young group had the largest proportion of liver metastases (35.2% vs. 28.2% vs. 21.1%, p < 0.001), and elde

SUBMITTER: Sun S 

PROVIDER: S-EPMC10557883 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature