Regulatory effects of Zishen Yutai Pill on endometrial epithelial response in vitro in immunology microenvironment.

ABSTRACT:

Objective

Zishen Yutai Pill (ZYP) is a frequently used traditional Chinese medicine (TCM) preparation in women's health. However, the effects of ZYP on endometrial epithelial response have not been fully explored. Herein, uterine natural killer cell (uNK) secretion medium was used to mimic the uterine microenvironment. Thereafter, an endometrial epithelial cell line (Ishikawa cells) was treated with ZYP-containing serum to elucidate the effects of ZYP on endometrial receptivity.Methods: uNK cells were isolated from decidual tissues of pregnant women undergoing pregnancy termination surgery, and thereafter, uNK secretion medium was collected. ZYP-containing serum was collected from rats after intragastrical administration of ZYP. Ishikawa cells were divided into three groups, one tr

SUBMITTER: Chen X 

PROVIDER: S-EPMC10558344 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature