A systematic review on the performance of fracture risk assessment tools: FRAX, DeFRA, FRA-HS.

ABSTRACT:

Purpose

Preventing fragility fractures by treating osteoporosis may reduce disability and mortality worldwide. Algorithms combining clinical risk factors with bone mineral density have been developed to better estimate fracture risk and possible treatment thresholds. This systematic review supported panel members of the Italian Fragility Fracture Guidelines in recommending the use of best-performant tool. The clinical performance of the three most used fracture risk assessment tools (DeFRA, FRAX, and FRA-HS) was assessed in at-risk patients.

Methods

PubMed, Embase, and Cochrane Library were searched till December 2020 for studies investigating risk assessment tools for predicting major osteoporotic or hip fractures in patients with osteoporosis or fragility fractures. Sensit

SUBMITTER: Adami G 

PROVIDER: S-EPMC10558377 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature