Development and Validation of the Veterans Affairs Eosinophilic Esophagitis Cohort.

ABSTRACT:

Background & aims

Gaps remain in understanding the epidemiology of eosinophilic esophagitis (EoE). Our aim was to identify and validate a national cohort of individuals with EoE using Veterans Health Administration (VHA) data.

Methods

We used 2 validation strategies to develop algorithms that identified adults with EoE between 1999 and 2020. The first validation strategy applied International Classification of Diseases (ICD) code algorithms to a base cohort of individuals who underwent esophagogastroduodenoscopy with esophageal biopsy specimens. The second applied ICD code algorithms to a base cohort of all individuals in the VHA. For each ICD algorithm applied, a random sample of candidate EoE cases and non-EoE controls were selected and the charts were reviewed manually by

SUBMITTER: Low EE 

PROVIDER: S-EPMC10558623 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature