Ontology highlight
ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC10558642 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Liu Lulu L Pang Jiaojiao J Qin Dandan D Li Ruochuan R Zou Dan D Chi Kai K Wu Wenxiao W Rui Haiying H Yu Huaxiang H Zhu Wenyong W Liu Kai K Wu Xuting X Wang Jinxin J Xu Ping P Song Xiaoshuai X Cao Yihai Y Wang Jiali J Xu Feng F Xue Li L Chen Yuguo Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20230808 28
Despite the development of advanced technologies for interventional coronary reperfusion after myocardial infarction, a substantial number of patients experience high mortality due to myocardial ischemia-reperfusion (MI/R) injury. An in-depth understanding of the mechanisms underlying MI/R injury can provide crucial strategies for mitigating myocardial damage and improving patient survival. Here, it is discovered that the 4-hydroxy-2-nonenal (4-HNE) accumulates during MI/R, accompanied by high r ...[more]