The impact of fibronectin knockout on invasion and migration of endometrial cell in adenomyosis.
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ABSTRACT:
SUBMITTER: Gao J
PROVIDER: S-EPMC10558947 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
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The impact of fibronectin knockout on invasion and migration of endometrial cell in adenomyosis.
Gao Jiangman J Guo Wei W Li Rong R Qiao Jie J Long Xiaoyu X
Heliyon 20230830 9
The present study aimed to investigate the potential effect of fibronectin (FN) in adenomyosis progression. Small guide RNAs were designed to knock down FN expression in Ishikawa cells. The impact of FN on the proliferation, apoptosis, migration, and invasion of the cells was assessed. Cell proliferation was detected using a Celigo Imaging Cytometer system; apoptosis was quantified by flow cytometry; and cell migration and invasion were investigated via transwell assays. Cell proliferation was m ...[more]
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