EEG functional connectivity in infants at elevated familial likelihood for autism spectrum disorder.

ABSTRACT:

Background

Many studies have reported that autism spectrum disorder (ASD) is associated with atypical structural and functional connectivity. However, we know relatively little about the development of these differences in infancy.

Methods

We used a high-density electroencephalogram (EEG) dataset pooled from two independent infant sibling cohorts, to characterize such neurodevelopmental deviations during the first years of life. EEG was recorded at 6 and 12 months of age in infants at typical (N = 92) or elevated likelihood for ASD (N = 90), determined by the presence of an older sibling with ASD. We computed the functional connectivity between cortical sources of EEG during video watching using the corrected imaginary part of phase-locking values.

Results

Our main an

SUBMITTER: O'Reilly C 

PROVIDER: S-EPMC10559476 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature