A pretreatment prediction model of grade 3 tumors classed by the IASLC grading system in lung adenocarcinoma.

ABSTRACT:

Purpose

The new grading system for invasive nonmucinous lung adenocarcinoma (LUAD) in the 2021 World Health Organization Classification of Thoracic Tumors was based on a combination of histologically predominant subtypes and high-grade components. In this study, a model for the pretreatment prediction of grade 3 tumors was established according to new grading standards.

Methods

We retrospectively collected 399 cases of clinical stage I (cStage-I) LUAD surgically treated in Tianjin Chest Hospital from 2015 to 2018 as the training cohort. Besides, the validation cohort consists of 216 patients who were collected from 2019 to 2020. These patients were also diagnosed with clinical cStage-I LUAD and underwent surgical treatment at Tianjin Chest Hospital. Univariable and multivari

SUBMITTER: Wang K 

PROVIDER: S-EPMC10559613 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature