Circulating biomarkers of cardiovascular disease are related to aneurysm volume in abdominal aortic aneurysm.

ABSTRACT:

Background

Surveillance programs in abdominal aortic aneurysms (AAA) are mainly based on imaging and leave room for improvement to timely identify patients at risk for AAA growth. Many biomarkers are dysregulated in patients with AAA, which fuels interest in biomarkers as indicators of disease progression. We examined associations of 92 cardiovascular disease (CVD)-related circulating biomarkers with AAA and sac volume.

Methods

In a cross-sectional analysis, we separately investigated (1) 110 watchful waiting (WW) patients (undergoing periodic surveillance imaging without planned intervention) and (2) 203 patients after endovascular aneurysm repair (EVAR). The Cardiovascular Panel III (Olink Proteomics AB, Sweden) was used to measure 92 CVD-related circulating biomarkers. We

SUBMITTER: Bouwens E 

PROVIDER: S-EPMC10559648 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature