Epileptic seizures at multiple sclerosis onset and their role in disease progression.

ABSTRACT:

Background

Epileptic seizures can occur throughout the course of multiple sclerosis (MS) and are associated with increasing disability progression over time. However, there are no data on whether epileptic seizures at the onset of MS also lead to increasing disability.

Objective

To examine disease progression over time for MS patients with epileptic seizures at onset.

Methods

We analyzed the data of 30,713 patients on the German Multiple Sclerosis Register in a case-control study for more than 15 years. MS patients with seizures at onset were further divided into subgroups with polysymptomatic and monosymptomatic onset to assess the impact of additional symptoms on disease progression.

Results

A total of 46 patients had seizures as onset symptoms. Expanded Disa

SUBMITTER: Grothe M 

PROVIDER: S-EPMC10559692 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature