Association between platelet to lymphocyte ratio and depression and symptom severity among adults in the United States: A cross-sectional study.

ABSTRACT:

Background

The pathogenesis of depression has not yet been fully understood. The association between platelet to lymphocyte ratio (PLR) and depression has been investigated in previous studies, however, the results were controversial. The objective of the study was to explore the potential relationship between PLR and depression and symptom severity.

Methods

A cross-sectional study was conducted based on the National Health and Nutrition Examination Survey (NHANES) data from 2005 to 2018. Totally 30,032 adults were analyzed, and 2480 reported depression. Depression and symptom severity were assessed with the Patient Health Questionnaire (PHQ-9). PLR was calculated as the ratio of platelets to lymphocytes. Multivariable weighted-logistic regression models and generalized addi

SUBMITTER: Shan M 

PROVIDER: S-EPMC10559847 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature