Association between acute liver injury & severity and mortality of COVID-19 patients: A systematic review and meta-analysis.

ABSTRACT:

Background

Acute liver injury (ALI), a complication often seen in COVID-19 patients, can lead to severe liver damage, multi-organ failure, acute vascular events, and can potentially escalate to patient mortality. Given this, we initiated a meta-analysis to investigate the correlation between ALI and adverse outcomes in COVID-19 patients.

Methods

We conducted an exhaustive search of databases, including Medline, Embase, PubMed Central, ScienceDirect, Google Scholar, and the Cochrane Library, from the November 2019 until January 2022. The quality of the included studies was evaluated using the Newcastle Ottawa (NO) scale. Our meta-analysis was carried out using a random-effects model and results were presented as pooled odds ratios (ORs) with their corresponding 95% confidence

SUBMITTER: Krishnamoorthy Y 

PROVIDER: S-EPMC10560047 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature