Associations of continuous anionic gap detection with the mortality in critically ill patients receiving renal replacement therapy.

ABSTRACT:

Purpose

To investigate the associations of anion gap (AG) levels before and 1-day after hemodialysis as well as anion gap changes with the mortality in critically ill patients receiving renal replacement therapy (RRT).

Methods

Totally, 637 patients from MIMIC-III were included in this cohort study. The associations between AG (T0), AG (T1), or ∆AG [AG (T0) - AG (T1)], and the risk of 30-day or 1-year mortality were examined by Cox restricted cubic spline regression models. Univariate and multivariate Cox proportional-hazards model was applied to assess the associations between AG (T0), AG (T1), ∆AG with 30-day and 1-year mortality, respectively.

Results

The median follow-up time was 18.60 (8.53, 38.16) days and 263 (41.3%) patients were survived. There was a linear re

SUBMITTER: Zhai Y 

PROVIDER: S-EPMC10560184 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature