Balanced crystalloid solutions versus normal saline in intensive care units: a systematic review and meta-analysis.

ABSTRACT:

Background

Intravenous fluid therapy is important for pediatric and adult patients in intensive care units (ICUs). However, medical professionals continue to struggle to determine the most appropriate fluids to obtain the best possible outcomes for each patient.

Objective

We conducted a meta-analysis involving cohort studies and randomized controlled trials (RCTs) to compare the influence of balanced crystalloid solutions and normal saline among patients in ICUs.

Patients and methods

Studies that compared balanced crystalloid solutions and saline in ICU patients from databases including PubMed, Embase, Web of Science, and Cochrane Library were systematically searched up to July 25, 2022. The primary outcomes were mortality and renal-related outcomes, which included ma

SUBMITTER: Wang P 

PROVIDER: S-EPMC10560196 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature