Functional neuroimaging of responses to multiple sensory stimulations in newborns with perinatal asphyxia.

ABSTRACT:

Background

Functional neuroimaging can provide pathophysiological information in perinatal asphyxia (PA). However, fundamental unresolved questions remain related to the influence of neurovascular coupling (NVC) maturation on functional responses in early development. We aimed to probe the feasibility and compare the responses to multiple sensory stimulations in newborns with PA using functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS).

Methods

Responses to visual, auditory, and sensorimotor passive stimulation were measured with fMRI and fNIRS and compared in 18 term newborns with PA and six controls.

Results

Most newborns exhibited a positive fMRI response during visual and sensorimotor stimulation, higher in the sensorimot

SUBMITTER: Pinto CR 

PROVIDER: S-EPMC10560353 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature