A novel laboratory-based nomogram for assessing infection presence risk in acute-on-chronic liver failure patients.

ABSTRACT: Accurate assessment of infection presence risk level, timely diagnosis, and effective control are critical for decreasing mortality of Acute‑on‑chronic liver failure (ACLF). We aimed to develop and validate a novel diagnostic model to accurately assess infection presence risk level in ACLF patients. 185 ACLF patients with/without infection were enrolled, and their demographic, physical findings, immune-inflammatory, hepatic function, metabolism, and coagulation-fibrinolysis indicators were analyzed. Regression analysis was performed to identify the independent diagnostic parameters, which were further used to establish diagnostic models with a nomogram for visual. An area under receiver operating characteristic curve (AUROC), calibration plots, clinical impact curves, decision curve analys

SUBMITTER: Sun R 

PROVIDER: S-EPMC10560663 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature