Morphological features of the photoplethysmographic signal: a new approach to characterize the microcirculatory response to photobiomodulation.

ABSTRACT: Introduction and Objectives: Advanced analysis of the morphological features of the photoplethysmographic (PPG) waveform may provide greater understanding of mechanisms of action of photobiomodulation (PBM). Photobiomodulation is a non-ionizing, red to near-infrared irradiation shown to induce peripheral vasodilatation, promote wound healing, and reduce pain. Using laser Doppler flowmetry combined with thermal imaging we found previously in a clinical study that PBM stimulates microcirculatory blood flow and that baseline palm skin temperature determines, at least in part, why some individuals respond favorably to PBM while others do not. "Responders" (n = 12) had a skin temperature range of 33°C-37.5°C, while "non-responders" (n = 8) had "cold" or "hot" skin temperature (<33°C or >

SUBMITTER: Ovadia-Blechman Z 

PROVIDER: S-EPMC10561251 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature