Proton Beam Therapy versus Radiofrequency Ablation for Patients with Treatment-Naive Single Hepatocellular Carcinoma: A Propensity Score Analysis.

ABSTRACT:

Introduction

Proton beam therapy (PBT) is known to be an effective locoregional treatment for hepatocellular carcinoma (HCC). However, few comparative studies in treatment-naïve cases have been reported. The aim of this study was to compare the survival outcomes of PBT with those of radiofrequency ablation (RFA) in patients with treatment-naïve solitary HCC.

Methods

Ninety-five consecutive patients with treatment-naïve HCC, a single nodule measuring ≤5 cm in diameter, and a Child-Pugh score of ≤8 who were treated with PBT at the University of Tsukuba Hospital between 2001 and 2013 were enrolled in the study. In addition, 836 patients with treatment-naïve HCC treated by RFA at the University of Tokyo Hospital during the same period were analyzed as controls. Recurrence-free s

SUBMITTER: Sekino Y 

PROVIDER: S-EPMC10561322 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature