Rationale of the PAPAartis trial.

ABSTRACT: Surgical and interventional repair of thoracoabdominal aortic aneurysms improve survival significantly compared to the natural history of the disease. However, both strategies are associated with a substantial risk of spinal cord ischemia, which has been reported to occur-even in contemporary series by expert centers-in up to 12% of patients, depending on the extent of the disease. Following improved neurological outcomes after staged approaches in extensive clinical and long-term large animal studies, and the description of the "collateral network", the concept of "Minimally Invasive Staged Segmental Artery Coil Embolization" (MIS²ACE) was introduced by Etz et al. This concept of priming the collateral network in order to improve spinal cord blood supply showed promising

SUBMITTER: Misfeld M 

PROVIDER: S-EPMC10561337 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature