Breast cancer risk factors and mammographic density among 12518 average-risk women in rural China.

ABSTRACT:

Background

Mammographic density (MD) is a strong risk factor for breast cancer. We aimed to evaluate the association between MD and breast cancer related risk factors among average-risk women in rural China.

Methods

This is a population-based screening study. 12518 women aged 45-64 years with complete MD data from three maternal and childcare hospitals in China were included in the final analysis. ORs and 95%CIs were estimated using generalized logit model by comparing each higher MD (BI-RADS b, c, d) to the lowest group (BI-RADS a). The cumulative logistic regression model was used to estimate the OR_trend (95%CI) and P_trend by treating MD as an ordinal variable.

Results

Older age (OR_trend = 0.81, 95%CI: 0.79-0.81, per 2-year increase)

SUBMITTER: Yan H 

PROVIDER: S-EPMC10561452 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature